Laboratory animals and analgesia: the responsibility of ethics committees and the obligations of researchers

Authors

  • Caio Vinicius Botelho Brito Universidade do Estado do Pará - UEPA
  • Rosa Helena de Figueiredo Chaves Soares
  • Nara Macedo Botelho

Abstract

The aim of the present study was to evaluate projects submitted to an Animal Research Ethics Committee regarding the use of analgesia in experimental surgery. A total of 106 projects submitted to the Animal Research Ethics Committee were evaluated and the following information was collected: methodology of the surgical procedure, use of analgesia, justification of the non-use of analgesia and application of the degree of invasiveness. Of the projects evaluated, 64.2% used surgical techniques, of which 65.6% did not use analgesia postoperatively, with the main reason being that the analgesic could alter the results. In 17% of cases the classification of the degree of invasiveness was used in an irregular manner. The stimulation and dissemination of analgesia-related knowledge must stem from both the ethics committees responsible and researchers.

Keywords:

Bioethics. Laboratory animals. Experimental surgery.

Author Biography

Caio Vinicius Botelho Brito, Universidade do Estado do Pará - UEPA

Médico formado pelo Centro Universitario do Estado do Pará, Mestrando do Programa de Cirurgia e Pesquisa Experimental da Universidade do Estado do Pará.
Vol. 24 No. 3 (2016): Rev. bioét. (Impr.). 2016; 24 (3)

Published:

2016-11-25

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How to Cite

1.
Brito CVB, Soares RH de FC, Botelho NM. Laboratory animals and analgesia: the responsibility of ethics committees and the obligations of researchers. Rev. bioét.(Impr.). [Internet]. 2016 Nov. 25 [cited 2024 May 13];24(3). Available from: https://revistabioetica.cfm.org.br/revista_bioetica/article/view/1162